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Fachpublikationen, Anwendungen und wissenschaftliche Beiträge aus der LUM Literaturdatenbank.

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3140 Ergebnisse

Quantitative Assessment of Ceramic Suspension Stability Using a LUMiSizer Analytical Centrifuge

Autor
Patrik Sokola, Tina Skalar, Pavel Šiler, Jan Blahut, Michal Kalina, Peter Veteška and Petr Ptáˇcek
Jahr
2025
Quelle
Ceramics
Sprache
English
Seiten
115
  • 3144
  • LS
  • LUMiSizer
  • sedimentation; instability index; effect of additives; dispersion media; dispersant concentration; metakaolin; corundum; zirconia
2 weitere
  • Al2O3
  • ZrO
Weitere Details
Ausgabe
8
Interne Referenz
3144
Veröffentlichung öffnen

Real-time testing & consolidation fingerprinting using X-radiation extend knowledge in formulation, processing & QC - Odborný seminář: Rentgenový sedimentační analyzátor LUMiReader

Autor
A. Uhl in collaboration with Anamet S.r.o.
Jahr
2025
Quelle
Webinar
Sprache
English
  • 3063
  • LUMiReader X-Ray
  • LRX
  • Direct real-time analysis using X-Ray
25 weitere
  • Consolidation using X-Ray
  • Multistep Analysis
  • Combination
  • Particle dispersibility
  • formulation homogeneity by X-ray transmission
  • ZnO
  • make-up
  • hpc
  • cosmetics
  • personal care
  • cream
  • dispersibility of an inorganic filler in a polymer foam
  • Overcome the limitation of optical wavelengths for solutions
  • NaCl
  • sodium chloride
  • Iron(III) nitrate nonahydrate solution
  • Dispersibility of dry TiO2 into other powders
  • 20 w/w% CaCO3 dispersed into a polymer matrix
  • Real-time separation of ceramic samples
  • Battery slurries - sedimentation rate vs. mixing time (energy entry)
  • Creams of unknown composition –Be the first to see changes
  • Lacquers for dental applications
  • facial clay masks
  • LUMiSizer
  • LS
Weitere Details
Ausgabe
12 March 2025
Ort
www.dispersion-letters.com
Interne Referenz
3063
Veröffentlichung öffnen

Rheological properties of stirred-type yogurt containing pea protein regulated by welan gum: Implications for dysphagia-targeted medical foods

Autor
Yalong Guo, Ziyu Zhou, Qingyu Liao, Huimin Ren, Yixin Wang, Aiqin Ma, Hongbin Zhang
Jahr
2025
Quelle
Food Hydrocolloids
Sprache
English
Seiten
111435
  • 3130
  • LS
  • LUMiSizer
  • LUMiSizer stability analysis Whey separation (wheying-off)
10 weitere
  • the appearance of whey liquid on the surface of yogurt gel
  • is one of the most common quality defects in yogurt products (Lucey
  • 2004). Compared to set yogurt
  • stirred yogurt is more prone to whey separation due to the mechanical homogenization process
  • which disrupts the original network structure of the yogurt. This makes whey separation more likely to occur (Matumoto-Pintro et al.
  • 2011). In this study
  • the effect of adding different concentrations of Welan gum
  • food
  • nutrition
  • dairy
Weitere Details
Ausgabe
167
Interne Referenz
3130
Veröffentlichung öffnen

Sex-Based Differences in the In Vitro Digestibility of MCT Emulsions Stabilized by Various Emulsifiers

Autor
Mijal Perez, Carmit Shani Levi and Uri Lesmes
Jahr
2025
Quelle
Foods
Sprache
English
Seiten
131
  • 3021
  • emulsions; sex differences; in vitro digestion; medium-chain triglycerides; protein and non-protein emulsifier
  • LUMiSizer
  • LS
1 weitere
  • Physical Stability Assessment of Emulsions Using Analytical Centrifugation The physical stability of emulsions was evaluated using an analytical centrifuge LUMisizer
Weitere Details
Ausgabe
14
Interne Referenz
3021
Veröffentlichung öffnen

Stability and Rheological Properties of the Novel Silica-Based Organogel—A Drug Carrier with High Solubilization Potential

Autor
Grzegorz Suwinski and Izabela Nowak
Jahr
2025
Quelle
Materials
Sprache
English
Seiten
266
  • 3026
  • LS
  • LUMSizer
  • silica; organogel; drug delivery carrier; solubilization; cosmetic
13 weitere
  • hpc
  • Dissolution of a poorly soluble active pharmacological substance in a drug carrier usually requires advanced techniques and production equipment. The use of novel carriers such as microemulsions
  • vesicles
  • or nanocarriers might entail various limitations concerning production cost
  • formulation stability
  • or active substance capacity. In this paper
  • we present a novel fumed silica-based organogel as a low-cost
  • simple preparation drug or cosmetic carrier with interesting rheological properties and high solubilization capacity
  • Particle size distribution. Volume-weighted particle size distribution was measured on LUMiSizer
  • psd
  • psa
  • analysis
  • Przedsiębiorstwo Farmaceutyczne Farmapol
Weitere Details
Ausgabe
18
Interne Referenz
3026
Veröffentlichung öffnen

Statistical simplex centroid experimental design and formulation maps to predict the stability in cosmetic emulsions containing commercial emulsifiers

Autor
Angela Mazabel Rios, Juanita Pulido Teuta, Liliam A. Palomeque, Ramon E. Vera, Ronald Marquez,| Johnbrynner García
Jahr
2025
Quelle
J Surfact Deterg.
Sprache
English
Seiten
1–15
  • 3102
  • LS
  • home and persnal care
  • hpc
39 weitere
  • Belcorp Research
  • Development & Innovation
  • Tocancipa
  • Colombia 2 Department of Chemistry
  • Universidad Nacional de Colombia
  • Bogota
  • Colombia 3 Department of Forest Biomaterials
  • North Carolina State University
  • Raleigh
  • North Carolina
  • USA 4 Department of Chemical Engineering
  • Agricultural and Agrifood Technology
  • University of Girona
  • Girona
  • Spain
  • cosmetic
  • emollients
  • emulsion
  • formulation maps
  • LUMiSizer
  • stability
  • texture
  • Formulating cosmetic products to meet consumer expectations poses significant challenges in terms of stability and shelf life. This work evaluates cosmetic emul- sions formulated with three commercial emulsifiers: Polyglyceryl-3 distearate (Dermofeel®
  • a biobased surfactant)
  • Glyceryl stearate (50%)/PEG-100 stearate (50%) (Lipomulse®
  • a nonionic mixture of glyceryl and ethoxylated surfactants)
  • and Potassium cetyl phosphate (Amphisol K®
  • an anionic surfactant). Additionally
  • three emollients
  • namely Caprylic/Capric Triglyceride
  • Isoamyl Cocoate
  • and Jojoba Oil
  • were incorporated into the formulations. The effect of emulsion composition on stability
  • droplet size
  • rheology
  • and texture was systematically assessed via experiments and multivariate regression modeling
  • thereby providing an objective tool for cosmetic emulsions formulation.
  • stability of emulsions was assessed using the separation velocity and instability index
  • determined through analytical centrifugation with a LUMiSizer®
Weitere Details
Ausgabe
early view
Interne Referenz
3102
Veröffentlichung öffnen

StemCurCol – 3D printed scaffold for diabetic wound regeneration

Autor
Henrique Luis Piva, Mariana Santos de Queiroz, Flavia Sayuri Matsuo, Hiago Salge Borges, Mariana Kiomy Osako, Antonio Claudio Tedesco
Jahr
2025
Quelle
Annals of 3D Printed Medicine
Sprache
English
Seiten
100203
  • LS
  • LUMiSizer
  • 3123
  • 3D printing
16 weitere
  • Diabetes
  • Scaffold
  • Collagen
  • Diabetic wounds
  • particularly diabetic foot ulcers
  • pose a significant challenge for treatment due to impairedhealing and susceptibility to complications. The complex pathophysiology of wounds involves dysregulated cellular and molecular processes. Advanced therapeutic strategies are needed to address the different stages of wound healing. Curcumin
  • a natural polyphenol
  • has been shown to enhance epidermal re-epithelialization
  • mobilize cellular participants in wound repair
  • and improve different stages of wound healing. In this work curcumin-chitosan nanoparticles have been prepared and characterized
  • and incorporated in collagen with stem cells and were implanted into normal and diabetic mice with induced wounds and their effects on wound healing were evaluated over 14 days. pharmaceutical
  • medical
  • Accelerated stability tests were performed using a LUMiSizer® analyzer
  • Data were obtained in the near-infrared region (NIR) with a centrifugal force of 87 g at 25 ◦C
  • and the transmission profiles were recorded for 8 h
  • simulating a one-year shelf life.
Weitere Details
Ausgabe
18
Interne Referenz
3123
Veröffentlichung öffnen

Structure and Rheology of Polymer-based Emulsions in Common Solvent Stabilized by Copolymers

Autor
Hyun Jung Lee
Jahr
2025
Quelle
THESE DE DOCTORAT
Sprache
English
Seiten
1-124
  • 3134
  • LUMiReader PSA
  • LRPSA
  • The emulsion stability of PS-PMMA emulsions in BE was assessed by measuring the transmission profile of the samples along tubes as a function of time under gravity using LUMiReader®
4 weitere
  • evolution of the transmission profile of the emulsion under gravity with time is shown in Figure 4-3
  • was measured using a LUMiReader
  • Chapter 4. Microstructure and Rheological properties of aging PS/PMMA-based All Non-aqueous Solvent Emulsions
  • transmission profile of the emulsion from the top (0%) to the bottom (100%) measured with the LUMiReader® under gravity at different aging times
Weitere Details
Ort
LE MANS UNIVERSITE, France
Interne Referenz
3134
Veröffentlichung öffnen

Study on the interactions and interfacial behaviors of cellulose nanocrystal/β-lactoglobulin complexes for pickering emulsions

Autor
Qi Wu, Xinna Hu, Shuyu Lu, Bo Xu, Chenyu Bai, Tao Ma, Yi Song
Jahr
2025
Quelle
Food Hydrocolloids
Sprache
English
Seiten
110539
  • LS
  • 3023
  • nutrition
  • Pickering emulsions have been widely used in the cosmetics
10 weitere
  • biomedicine
  • and food industries (Peito et al.
  • 2022; Rayees
  • Gani
  • Noor
  • Ayoub
  • & Ashraf
  • 2024). Unlike conventional emulsions that are stabilized by small-molecule surfactants
  • solid particles are used as stabilizers in Pickering emulsions. Later
  • we delved deeper into the physical stability of the dispersions using the LUMiSizer
Weitere Details
Ausgabe
158
Interne Referenz
3023
Veröffentlichung öffnen

Synergistic rheology of chia and aloe vera mucilage with Spirulina residue: Enhancing emulsion stability for sustainable food applications

Autor
Nuria Calero, Luis A. Trujillo-Cayado, Francisco Carrillo, Sonia Oliveira, Anabela Raymundo
Jahr
2025
Quelle
Journal of Molecular Liquids Volume 437, Part A
Sprache
English
Seiten
128306
  • 3119
  • LRPSA
  • LUMiReader PSA
  • Aloe vera mucilage
8 weitere
  • Chia mucilage
  • Emulsion
  • Spirulina residue
  • Algal oil Rheology
  • physical stability of the emulsions was evaluated using a LUMiReader®
  • This study was conducted in two phases to develop sustainable
  • plant-based food emulsions using chia and aloe vera mucilage combined with Spirulina residual biomass (SRB)
  • a protein-rich byproduct from phycocyanin extraction aimed at valorising industrial residues.
Weitere Details
Ausgabe
437 Part A
Interne Referenz
3119
Veröffentlichung öffnen

The impact of ink processing on key characteristics of platinum detachment and pore structure to optimize fuel cell performance

Autor
Amin Said Amin, Ricardo Martinez-Hincapié, Ali Raza Khan, André Olean-Oliveira, Ahammed Suhail Odungat, Annika Gurowski, Adarsh Jain , Lars Grebener, Azita Rezvani, Mohaned Hammad, Thomas Lange, Fatih Özcan, Viktor Colic, Doris Segets
Jahr
2025
Quelle
International Journal of Hydrogen Energy
Sprache
English
Seiten
1240-1256
  • 3077
  • LUMiFrac
  • LFrac
  • Wet impact mill
11 weitere
  • Platinum detachment
  • Pore structure
  • Particle size
  • ORR activity
  • Electrochemical performance
  • Analytical centrifugation (AC): All sedimentation studies were conducted with the LUMisizer
  • LS
  • batter
  • energy
  • Centrifugal detachment
  • The LUMiFrac (LUM GmbH) has been used to determine the adherence of the CLs on the PTFE substrate
Weitere Details
Ausgabe
144
Interne Referenz
3077
Veröffentlichung öffnen

Über anzahlbasierte Referenzmaterialien für die Charakterisierung von nanoskaligen Partikeln - Herausforderung Nanopartikelanalytik

Autor
Dr. Matthew A. Hood, Dr. Susan Strohschein-Lerche
Jahr
2025
Quelle
https://www.labo.de/optische-analysengeraete/nanopartikelanalytik--bedeutung-anzahlbasierter-referenzmaterialien-fuer-die-charakterisierung-von-nanoskaligen-partikeln.htm?utm_source=Partikelanalyse&utm_medium=Newsletter&utm_campaign=Labo&utm_content=LA_Standard&liana_pv=ec6a0bc2e64ccb1c7fc2b944a7bc3447
Sprache
German
Seiten
1-7
  • 3073
  • LSpoc
  • LUMiSpoc
  • Natürliche Materialien im Submikrometer- und Nanometerbereich
2 weitere
  • Analyse des Referenzmaterials mittels Einzelpartikel-Analysesystem. Die Untersuchung von Stabilität und Homogenität während der Entwicklungsphase erfolgte beim Unternehmen Dr. Lerche unter Anwendung eines nach ISO 17025 akkreditierten Prüfverfahrens. Die Messungen erfolgten mit einem auf flowzytometrischer Technologie basierenden System von LUM. "Engineered Nanomaterials" (ENMs)
  • Die weiteren Messungen des Konzentrationsstandards und die statistischen Auswertungen erfolgten gemäß den Vorgaben der ISO 17034 und ISO Guide 35. Die Bestimmung von Partikelanzahlkonzentration und Partikelgröße erfolgte mit einem Einzelpartikel-Analysesystem basierend auf flowzytometrischer Grundlage (Hersteller: LUM). Die angewandte Methode zur Bestimmung der Partikelanzahlkonzentration ist beim Unternehmen Dr. Lerche Teil der Akkreditierung nach ISO 17025.
Weitere Details
Ausgabe
09.07.2025, 08:12
Interne Referenz
3073
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Ultrasound combined with pH-shifting improved the emulsification and stability of coconut meal protein isolate by modifying physicochemical properties and intermolecular forces

Autor
Jin Guo, Jiale He, Wenlin Xu, Zewei Ma, Rongli Li, Wenjie Xia, Xinpeng Bai, Zhaoxian Huang, Yan Tian, Hongjian Zhang
Jahr
2025
Quelle
Ultrasonics Sonochemistry
Sprache
English
Seiten
107436
  • 3182
  • LS
  • LUMiSizer
  • Coconut meal protein isolates Ultrasound combined with pH-shifting treat- ment Physicochemical properties Emulsion stability Viscosity
5 weitere
  • This study investigated the effects of ultrasound combined with acidic/alkaline pH-shifting (U-C/U-K) and acidic/alkaline pH-shifting combined with ultrasound (C-U/K-U) on the physicochemical properties and emul- sification performance of Coconut Meal Protein Isolate (CMPI). The results demonstrated that these modification treatments reduced the particle size and polydispersity index of CMPI
  • increased its net charge
  • and improved its solubility
  • except in the group subjected to the ultrasound followed by acid pH-shifting (U-C). Instability index The LUMiSizer stability analyzer
  • Emulsifying stability The centrifugation stability of CMPI emulsions was evaluated using a LUMiSizer dispersion analyzer.
Weitere Details
Ausgabe
120
Interne Referenz
3182
Veröffentlichung öffnen

Using the LUMiSpoc® single particle counter and sizer to develop Opti-Count® nanoscale number concentration reference materials

Autor
Matthew A. Hood and Elia Wollik
Jahr
2025
Quelle
Dispersion Letters
Sprache
English
Seiten
18-23
  • 3129
  • Opti-Count®
  • reference materials
  • reproducibility
14 weitere
  • nanoparticles
  • particle size distribution
  • number-weighted size
  • number concentration
  • static light scattering
  • Mie theory
  • single particle detection
  • LUMiSpoc®
  • single particle optical counting and sizing
  • SPLS technology®
  • Single Particle Light-Scattering technology
  • 400 nm surfactant free aqueous polystyrene particle suspensions
  • opticount
  • optikount
Weitere Details
Ausgabe
16
Interne Referenz
3129
Veröffentlichung öffnen

Verhinderung der Additivmigration in Polymerklebungen durch Atmosphärendruck-Plasmabeschichtungen

Autor
David Herbig, Sergey Stepanov, Michael Heilig, Annika Stalling, Eduard Kraus, Benjamin Baudrit, Thomas Hochrein, Martin Bastian
Jahr
2025
Quelle
Forschungsbericht Plasmaprotect
Sprache
German
Seiten
1-94
  • 3208
  • LFrac
  • LUMiFrac
  • Fraunhofer IFAM
10 weitere
  • SKZ
  • Im Verlauf des Projekts wurde ein Testverfahren zur Beurteilung der Spannungsrissempfindlichkeit von Kunststoffen gegenüber Klebstoffen und Primern entwickelt sowie kritische Verbundkombinationen gescreent. Anschließend wurden verschiedene Beschichtungssysteme abgeschieden
  • charakterisiert und getestet
  • wobei sich insbesondere SiOxbasierte Schichten als besonders effektiv gegenüber der Klebstoff-induzierten Schädigung erwiesen. Diese verbesserten sowohl die Spannungsrissbeständigkeit als auch die Haftfestigkeit signifikant. Barrierebeschichtungen auf Basis von amorphem Kohlenstoff hingegen zeigten eine gute Performance im Fall der Kunststoff-induzierten Schädigung. Im Rahmen des Forschungsprojekts PlasmaProtect wurde die Herausforderung der Additivmigration in Polymerklebverbindungen untersucht
  • die zu Spannungsrissen und Adhäsionsverlusten führen kann. Konkret wurden im Projekt zwei industriell bekannte Schadensfälle näher betrachtet: die Klebstoff- sowie die Kunststoffinduzierte Schädigung des Klebverbunds. Ziel des Projekts war es
  • durch den Einsatz von Atmosphärendruck-Plasmabeschichtungen wirksame Barriereschutzschichten zu generieren
  • durch welche die Additivmigration verhindert und somit die Langzeitstabilität von Klebverbindungen verbessert wird. Charakterisierung der Klebverbunde
  • Stirnabzugstests mittels Centrifugal Adhesion Testing
  • Für die Messung der Stirnabzugsfestigkeit kam die Centrifugal Adhesion Testing (CAT)- Technologie zum Einsatz
  • mit der bis zu acht Klebeproben auf einmal geprüft werden können
Weitere Details
Interne Referenz
3208
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Wetting Across the Lyophilic–Lyophobic Spectrum: Morphological Tuning of Anode Catalyst Layers for the Alkaline Oxygen Evolution Reaction

Autor
Adarsh Jain, Christian Marcks, Gereon Mahler, Ahammed Suhail Odungat, Lars Grebener, Jacob Johny, Mohit Chatwani, Abhishek Shaji, Tobias Melchert, Marc Frederic Tesch, Malte Behrens, Anna K. Mechler, Vineetha Vinayakumar, Doris Segets
Jahr
2025
Quelle
engineering archive engrxiv
Sprache
English
Seiten
1-37
  • 3079
  • In alkaline water electrolysis (AWE)
  • anode wettability plays a critical role in governing bubble dynamics at the anode–electrolyte interface. Effective bubble management is essential for improving AWE performance
  • as it enhances active site accessibility and reduces transport resistance. This study investigates the influence of super-lyophilicity and super-lyophobicity of spray-coated nickel iron layered double hydroxide (Ni-Fe-LDH) anodes on the electrochemical performance for the oxygen evolution reaction (OER). Ni-Fe-LDH
12 weitere
  • wettability
  • Wenzel model
  • Cassie-Baxter model
  • super- hydrophilicity
  • super-hydrophobicity
  • alkaline water electrolysis
  • LUMiSizer
  • LS
  • Ink characterization All inks were characterized by utilizing analytical centrifugation (Analytical Centrifuge LUMisizer)
  • Layer characterization
  • To quantify the adherence and coherence of the coatings under tensile stress
  • the centrifugal adhesion analyzer LUMiFrac® from the company LUM has been employed.
Weitere Details
Ausgabe
Preprint / Version 1
Interne Referenz
3079
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零脂果汁酸乳饮料的开发及稳定性分析 - Study on the Development and Stability of Zero Fat Fruit Juice Acidic Milk Beverage

Autor
FAN Jun-yan，LIU Hai-qing，ZHAO Shuang，HONG Peng，CHEN Jia，ZHANG Jia-jing，XIE Liu-jia， ZHANG Zhen-zhen，JIN Dan，FANG Ming
Jahr
2025
Quelle
饮 料 工 业
Sprache
Chinese
Seiten
1-10
  • 3190
  • LF
  • LUMiFuge
  • Hong Sheng Beverage Group Co.，Ltd.
7 weitere
  • food
  • nutrition
  • fruit juice acidic milk beverage; sensory; stabilizer
  • A zero-fat fruit juice acidic milk beverage was developed using skim milk powder，fruit juice and white sugar as the main ingredients. Single-factor and orthogonal experiments were conducted，with sensory evaluation as the primary criterion to determine the optimal formulation. Additionally， the impact of different stabilizer combinations on parameters such as centrifugation sedimentation rate， average particle size， and instability coefficient was analyzed to identify the best stabilizer solution. The results indicated that the optimal formula for the zero- fat fruit juice acidic beverage consisted of 2% milk powder， 8% white sugar， 0.22% citric acid， 1% concentrated fruit juice，and 0.008% acesulfame potassium. The most effective stabilizer combination was a 1∶1 ratio of standardized pectin to soluble soy polysaccharides，with an addition level of 0.4% . Under these conditions，the product exhibited the nutritional benefits and aroma of both milk and fruit juice，a refreshing taste，high sensory scores，and good stability. LS
  • LUMiSizer
  • 果汁酸性乳饮料；感官；稳定剂
  • 以脱脂奶粉、果汁、白砂糖等为主要原材料，进行零脂果汁酸乳饮料的开发。通过单因素实验和正交实验 方法，以感官评价为主要依据，确定最佳配方。同时，分析不同稳定剂组合对离心沉淀率、平均粒径及不稳定性系数 等参数的影响，从而筛选出最优的稳定剂方案。结果显示，零脂果汁酸乳饮料的最优配方为奶粉 2%、白砂糖 8%、 柠檬酸 0.22%、浓缩果汁 1%，安赛蜜 0.008%；最优稳定剂方案为果胶：可溶性大豆多糖=1∶1（添加量为 0.4%），此条 件下所得零脂果汁酸乳饮料兼具牛奶、果汁营养及香气，口感清爽，感官评分高，具备良好的稳定性。所得产品的蛋 白质含量为
Weitere Details
Ausgabe
with English abstract
Interne Referenz
3190
Veröffentlichung öffnen

30 years of LUM GmbH – Years of Flexibility, Innovation, Excellence and Reliable Partnership

Autor
Thomas Koch
Jahr
2024
Quelle
International Conference Dispersion Analysis & Materials Testing 2024
Sprache
English
Seiten
1
  • 2950
  • LUMiSizer
  • LUMiReader X-Ray
  • LS
12 weitere
  • LRX
  • titania
  • titanium dioxide
  • This short review over 10 years of fruitful bilateral industry cooperation between LUM and KRONOS INT. Inc.
  • development of a fast method for a plant applicable product nanoparticle characterisation of the products for food-
  • cosmetics- and pharma application
  • the sedimentation-based stability analysis of TiO2-pigment dispersions
  • the measurement of effective agglomerate densities of TiO2-pigments in dispersion and the development of HSP for TiO2-pigments
  • particle size distributions
  • psd
  • psa
  • particle size analysis
Weitere Details
Ausgabe
Abstracts
Ort
Berlin, Germany, 10-11 June 2024
Interne Referenz
2950
Veröffentlichung öffnen

A novel amphiphilic polyacrylate-cholesterol derivative as solubility enhancer and emulsion stabilizer for pharmaceutical and cosmetic applications

Autor
M. Viola, P. Matricardi, C. Di Meo, R. Cossi, C. Cencetti
Jahr
2024
Quelle
International Conference Dispersion Analysis & Materials Testing 2024
Sprache
English
Seiten
1-2
  • 2925
  • Polyacrylate-cholesterol derivative; Emulsion; Stability; Topical formulation; Solubility Enhancer
  • Polyacrylic acid (PAA) is a non-toxic
  • biocompatible
21 weitere
  • hydrophilic polymer that has gained increasing interest in the healthcare industry
  • Cholesterol (CH) is a vital substance in our body’s cells. In pharmaceutical and cosmetic applications
  • CH is used in different formulations due to its presence in human sebum and all the layers of the epidermis. For example
  • it can be incorporated into moisturizers
  • creams
  • and lotions to improve skin hydration by strengthening the skin’s natural barrier and reducing moisture loss. In pharmaceutics
  • when the skin barrier is compromised
  • CH-containing formulations can help restore and repair the barrier function
  • thereby alleviating symptoms and promoting healing. Furthermore
  • CH can be used to enhance the hydrophobic drugs’ solubility
  • and their penetration and absorption through the skin
  • aiding in effective drug delivery. The present work explores the potential for pharmaceutical applications of “PAAbCH”
  • an innovative amphiphilic polyacrylate grafted with CH moieties on its backbone. Due to the amphiphilic properties shown by this PAA derivative
  • its rheological behavior and its emulsifying action
  • our research focused on developing oil/water (O/W) emulsions for topical formulations
  • LumiSizer accelerated stability test profiles of PAAbCH-based emulsions at different sunflower oil concentrations
  • LS
  • hpc
  • pharmaceutical
  • home personal care
  • cosmetics
Weitere Details
Ausgabe
Abstracts
Ort
Berlin, Germany, 10-11 June 2024
Interne Referenz
2925
Veröffentlichung öffnen

A Procedure for Rational Probe Liquids Selection to Determine Hansen Solubility Parameters

Autor
Amin Said Amin, Dietmar Lerche, Ahammed Suhail Odungat, Sven Uwe Boehm, Thomas Koch, Fatih Özcan, and Doris Segets
Jahr
2024
Quelle
ChemCatChem
Sprache
English
Seiten
e202301393
  • Hansen Solubility Parameters (HSP)
  • viewed in the context of similarity whenever dispersion is focused
  • offer valuable insights into the surface characteristics of nanoparticles. However
  • existing methods for determining HSP via the sedimentation of nanoparticles require multiple probe liquids
19 weitere
  • resulting in timeconsuming
  • costly experiments with potential health risks. To address this
  • we developed a two-step strategy that enables a systematic selection of liquids
  • 2936
  • HDP
  • dispersibility
  • Formulation is essential in particle science and engineering for creating high-performance products. It is a crucial step in developing a wide range of products
  • including cosmetics
  • food
  • feed
  • pharmaceuticals
  • paints and varnishes
  • plastics
  • laminates and devices for renewable energy technologies like proton exchange membrane fuel cells (PEMFC)
  • or lithium-ion batteries (LIB). battery
  • energy storage
  • LUMiSizer
  • LS
  • Analytical centrifugation The LUMisizer analytical centrifuge was used for all sedimentation studies
Weitere Details
Interne Referenz
2936
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